- A dictionary of medical eponyms

Nissl's substance

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Chromophil substance in the form of granules found in the cell bodies and dendrites of neurons, but is absent from axons. They consist principally of the ribose type of nucleic acid and nucleoprotein and stain strongly with basic aniline dyes. They are concerned with protein synthesis and metabolism; their condition varies with physiological and pathological conditions.


  • F. Nissl:
    Über die sogenannten Granula der Nervenzellen.
    Neurologisches Centralblatt, Leipzig, 1894, 13: 676-685, 781-789, 810-814.
We thank Rudolf Kleinert, Bad Reichenhall, Germany, for submitting bibliographic information.

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