Silver-Russell syndrome (Alexander Russell)

Alternative eponyms

Related people

A syndrome of intra-uterine dwarfism with characterized by short stature, skeletal asymmetry, triangular shaped head and other anomalies.

Description

A syndrome of intra-uterine dwarfism with low birth weight characterized by short stature, skeletal asymmetry, relatively large skull with triangular shaped head, small incurved little fingers, characteristic facies, precocious sexual development. Renal and/or ureteral defects and mental retardation may occur in some cases. Café au lait macules are present in nearly half the cases. Nephroblastoma can be a complication. No sex preponderance. The mode of inheritance is unknown.

Some authors separate the Russell and Silver syndromes as independent entities, the Russell syndrome being a similar disturbance, but not asymmetric. However, Russell's and Silver's are now considered the same entity. An affected individual is known as the Russell dwarf.

Bibliography

  • H. K. Silver, W. Kiyasy, J. George, W. C. Deamer:
    Syndrome of congenital hemihypertrophy, shortness of stature, and elevated urinary gonadotropins.
    Pediatrics, Evanston, Illinois, 1953, 12: 368-375.
  • A. Russell:
    A syndrome of "intra-uterine" dwarfism recognizable at birth with cranio-facial dysostosis, disproportionately short arms and other anomalies (5 examples).
    Proceedings of the Royal Society of Medicine, London, 1954, 47: 1040-1044.
  • H. K. Silver:
    Asymmetry, short stature and variations in sexual development: a syndrome of congenital malformations.
    American Journal of Diseases of Children, Chicago, 1964, 107: 495-515.

What is an eponym?

An eponym is a word derived from the name of a person, whether real or fictional. A medical eponym is thus any word related to medicine, whose name is derived from a person.

What is Whonamedit?

Whonamedit.com is a biographical dictionary of medical eponyms. It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person.

Disclaimer:

Whonamedit? does not give medical advice.
This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor.