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Brown-McLean syndrome (S. I. Brown)

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    A syndrome of peripheral corneal oedema that involves the peripheral 2.0 to 3.0 mm of cornea, sparing the central cornea. Is usually occurs after surgery, particularly intracapsular cataract extraction, but some rare cases have been reported in patients with other predisposing factors. Severe myopia is a frequent complication.


    • S. I. Brown, J. M. McLean:
      Peripheral corneal edema after cataract extraction. A new clinical entity.
      Transactions of the American Academy of Ophthalmology and Otolaryngology, Rochester, 1969, 73: 465.
    • T. W. Gothard, D. R, Hardten, S. S. Lane, D. J. Doughman, J. H. Krachmer, E. J. Holland:
      Clinical findings in Brown-McLean syndrome.
      American Journal of Ophthalmology, Chicago, June 15, 1993, 115 (6): 729-737.

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