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Cori ester


Associated persons:
Carl Ferdinand Cori
Gerty Theresa Radnitz Cori

Description:
Glucose-1-phosphate (phosphate bound to a specific carbon atom on the glucose molecule). They demonstrated that it represents the first step in the conversion into glucose of the animal storage carbohydrate glycogen, large quantities of which are found in the liver, and--because the reaction is reversible--in some cases the last step in the conversion of blood glucose to glycogen. This ester along with the understanding of the action of the enzyme phosphorylase to produce the ester gave the foundation for sugar metabolism and storage in the body.

 
 

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