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Jaffe-Campanacci syndrome

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A syndrome of unknown etiology with variable expression characterized mainly by multiple non-ossifying fibromata, extraskeletal congenital anomalies such as café-au-lait spots, mental retardation, hypogonadism or cryptorchidism, and ocular and cardiovascular malformations.


  • H. L. Jaffe:
    Non-ossifying fibromata.
    In: H. L. Jaffe, editor: Tumors and Tumorous Conditions of the Bones and Joints. Philadelphia, Lea & Febiger, 1958, pp 117-141.
  • J. M. Mirra et al:
    Multiple Disseminated non-ossifying fibromas in association with café-au-lait spots (Jaffe-Campanacci syndrome).
    Clinical Orthopaedics, Philadelphia, 1982, 168: 192-205.
  • M. Campanacci al.
    Multiple non-ossifying fibromata with extraskeletal anomalies: A new syndrome.
    The Journal of Bone and Joint Surgery, London, 1983, 65(B):627-32.

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