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Campanacci's syndrome

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A syndrome of osteofibrous dysplasia of the tibia and fibula. It manifests as antero-lateral bowing of the shins, with osteolytic and sclerotic changes in the bony cortices. The pathogenesis is unknown. The term osteofibrous dysplasia was proposed by Campanacci in 1976 because of the congenital origin of the lesion, histologic resemblance to fibrous dysplasia and exclusive occurrence in the tibia and fibula. The report by Campanacci and Laus in 1981 was based on 35 cases.


  • M. Campanacci:
    Osteofibrous dysplasia of long bones. A new clinical entity.
    Italian Journal of Orthopaedics and Traumatology, 2: 221-237, 1976.
  • M. Campanacci, M. Laus:
    Osteofibrous dysplasia of the tibia and fibula.
    The Journal of Bone and Joint Surgery, Boston, 1981, 63A (3): 367-375.

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