Rule derived from the course of infection of malaria: the number of parasites in the red blood corpuscles in malaria is always determined by the severity of the malaria bout/attack. The attacks coincide in time with the sporulation of the parasites. The rule has not won general recognition and the terms seems to be rather unknown.
- C. Golgi:
Archivio per le scienze mediche, Torino, 1886; 10: 100-135.
Sul ciclo evolutivo dei parasiti malarica nella febre teriane.
Archivio per le scienze mediche, Torino, 1889; 13: 173-196.
Über die Wirkung des Chinins auf die Malariaparasiten und die diesen enstprechenden Fieberanfälle.
Deutsche medizinische Wochenschrift, Berlin, 1892, 18: 685-689, 701-709, 729-732.
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