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Magendie-Hertwig syndrome

Related people

Skew deviation of the eyes in acute cerebellar lesions. This rare syndrome relates to certain dissociated movements of the eyes which are sometimes associated with a cerebellar lesion, n. vestibularis and the connecting pathway between the eye muscles. It is characterized by a downward and inward rotation of the eyes on the side of the lesion and upward and outward deviation on the opposite side. The deviation is usually transient but may be seen in terminal states. The exact location of the lesion is not known, but it is thought to involve the middle cerebellar peduncle. Rotary nystagmus is common.

Reportedly, Magendie described this syndrome in 1833, but we are not sure about the reference.


  • Experimenta quaedam de efefctibus laesionum in partibus encephali singularibus et de verosimili harum partium functione.
    Berolini, formis Feisterianis et Eiserdorffianis [1926].
    In Cat Sur Gen, 1995, 1st series; 6: 185.
  • P. A. Jaensch:
    Bemerkungen zum Hertwig-Magendie Syndrom.
    Klinische Monatsblätter für Augenheilkunde, Stuttgart, 1958, 133: 866-869.

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