Michaelis-Menten hypothesis

Alternative eponyms

Related people

A general explanation of the velocity and gross mechanism of enzyme-catalysed reactions.

Description

A general explanation of the velocity and gross mechanism of enzyme-catalysed reactions. First stated in 1913, the hypothesis assumes that a complex is formed between an enzyme and its substrate, which complex then decomposes to yield free enzyme and the reaction product, the latter rate determine the overall rate of substrate-product conversion. The velocity of such a reaction is greatest when all the sites at which catalytic activity can take place on the enzyme molecules (active sites) are filled with substrate; i.e., when the substrate concentration is very high. These relationships provide the basis for all kinetic studies of enzymes and also have been applied to investigations of the effects of carriers upon the transport of substances through cell membranes.

The Michaelis-Menten mechanism for the catalysis of biological chemical reactions is one of the most important chemical reaction mechanisms in biochemistry.

What is an eponym?

An eponym is a word derived from the name of a person, whether real or fictional. A medical eponym is thus any word related to medicine, whose name is derived from a person.

What is Whonamedit?

Whonamedit.com is a biographical dictionary of medical eponyms. It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person.

Disclaimer:

Whonamedit? does not give medical advice.
This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor.