Michaelis-Gutmann body

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Basophilic inclusions in the cytoplasm containing calcium and iron seen in malacoplakia.

Description

Rounded lamellar basophilic inclusions in the cytoplasm containing calcium and iron seen in malacoplakia, a chronic infection characteristically in the renal tract. These inclusions are calcium and iron laden lyssosomes in large mononuclear cells called Hansemann’s Macrophages. Michaelis and Gutmann described malacoplakia in the urinary tract in 1902.

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