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Schwarts-Bartter syndrome (William Benjamin Schwartz)

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A syndrome of inappropriate secretion of antidiuretic hormone. Symptoms and signs include headache, confusion, disorientation, hostility and other mental aberrations without motor or sensory defects. Reflexes are normal and there is no dehydration or oedema, and no signs of renal, hepatic, or cardiac disease. It is found in association with various vasopressin-secreting tumours, with small-cell and oat-cell carcinomas of the lungs being the most frequent cause of this syndrome.

See also Bartter's syndrome, or primary juxtaglomerular cell hyperplasia with secondary hyperaldosteronism, under Frederic Crosby Bartter, American physician, 1914-1985.

Bibliography

  • A. Leaf, F. C. Bartter, R. F. Santos, et al:
    Evidence in man that urinary electrolyte loss induced by pitressin is function of water retention.
    Journal of Clinical Investigation, New York, 1953, 32: 868-878.
  • W. B. Schwartz, W. Bennett, S. Curelop, F. C. Bartter:
    A syndrome of renal sodium loss and hyponatriema probably resulting from inappropriate secretion of antidiuretic hormone.
    American Journal of Medicine, New York , 1957, 23: 529-542.
  • W. B. Schwartz, D. Tasssel, F. C. Bartter:
    Further observations on hyponatriema and renal sodium loss probably resulting from inappropriate secretion of antidiuretic hormone.
    New England Journal of Medicine, Boston, 1960, 262; 743-748.
  • F. C. Bartter, W. B. Schwartz:
    The syndrome of inappropriate secretion of antidiuretic hormone.
    American Journal of Medicine, New York, 1967, 42: 790-806.

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