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Dyke-Davidoff-Masson syndrome

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Cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses – resulting in facial asymmetry – and elevation of the sphenoid wing and petrous ridge, in association with contralateral hemiplegia, seizures, mental retardation, difficulty and impairment of speech development. Both sexes affected; present from birth. The condition is now believed to be caused by a vascular insult, more specifically an intrauterine or perinatal carotid artery infarction.

We thank Dr. Tariq Hakim, Islamabad, Pakistan, for information submitted.


  • C. G. Dyke, L. M. Davidoff, C. B. Masson:
    Cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses.
    Surgery, Gynecology and Obstetrics, Chicago, 1933, 57: 588-600.

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