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Samter's syndrome
Also known as:
Widal-Abrami-Lermoyez triad (M. Fernand Widal)
Widal-Lermoyez syndrome (M. Fernand Widal)
Widal's syndrome (M. Fernand Widal)
Associated persons:
Pierre Abrami
J. Lermoyez
Max Samter
M. Fernand Widal
Description:
A well-known syndrome in asthmatic and allergic diseases, characterised by the triad of bronchial asthma, vasomotor rhinitis, with or without nasal polyps, and intolerance to aspirin and aspirin-like medications. Associated features may include eosinophilia of bronchial and nasal secretions and of circulating blood, urticaria, and/or angioedema.
The aspirin triad syndrome was first described in 1922 by M. Fernand Widal, Pierre Abrami (1879-1945) and J. Lermoyez in 1922.
Bibliography:
- M. F. Widal, P. Abrami, J. Lermoyez:
Anaphylaxie et idiosyncrasie.
La presse médicale, Paris, 1922, 30: 189-192.
- M. Samter, R. F. Beers, Jr:
Concerning the nature of intolerance to aspirin.
Journal of Allergy, St. Louis, 1967, 40: 281-293.
- M. Samter, R. F. Beers, Jr:
Concerning the nature of intolerance to aspirin.
The Journal of Allergy, St, Louis, 1967, 40: 281.
- M. Samter, R. F. Beers, Jr:
Intolerance to aspirine; clinical studies and consideration of its pathogenesis.
Annals of Internal Medicine, Philadelphia, 1968, 68: 975-983.
- H. J. Zeitz, I. Jarmoszuk:
Nasal polyps, bronchial asthma, and aspirin insensitivity: The Samter syndrome.
Comprehensive Therapy, 1985, 11 (6): 21-25.
- M. Wayoff, et al:
Polypose naso-sinusienne et maladie à l’aspirine. Syndrome de Fernand Widal et Lermoyez.
Annales d'oto-laryngologie, Paris, 1979, 96: 229-239.
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