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Canale-Smith syndrome
Associated persons:
Virginia C. Canale
Carl Henry Smith
Description:
In most cases the disease picture of this syndrome is revealed early in life, usually before 5 years of age. Characteristic features include an afibrile chronic benign lymphadenopathy with immunoproliferative reaction, hypergammaglubulinaemia, and hepatosplenomegaly. The syndrome simulates malignant lymphoma.
Bibliography:
- V. C. Canale, C. H. Smith:
Chronic lymphadenopathy simulating malignant lymphoma.
Journal of Pediatrics, St. Louis, 1967, 70: 891-899.
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