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Cabot's ring bodies
Also known as:
Cabot's ring
Cabot-Schleip rings
Associated persons:
Richard Clarke Cabot
Karl Friedrich Wilhelm Schleip
Description:
They are delicate threadlike inclusions in the red blood cells in the peripheral blood of some patients with severe/megaloblastic anaemia. They may appear as rings, figures-of-eight, or twisted. They are blue-staining. Their origin is unknown. Contrary to Cabot’s belief, these structures have nothing to do with the nucleus or the nucleus’ membrane.
Bibliography:
- R. Clarke Cabot:
- A guide to the clinical examinations of the blood.
New York, 1896; 5th edition, 1904.
Ring bodies (nuclear remnants?) in anaemic blood. Journal of Medical Research, 1903, 9: 15-19.
- Karl Schleip:
Atlas der Blutkrankheiten.
Vienna, 1907; 2nd edition with Albert von Alder (1888-1951), Berlin and Vienna, 1928, translated into English.
Hematological atlas : with a description of the technic of blood examination.
By Priv. doz. Dr. Karl Schleip ; English adaptation of text, by Frederic E. Sondern ; with 71 coloured illustrations. New York : Rebman, 1908.
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