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Dejerine-Thomas atrophy

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A chronic progressive ataxia characterized by progressive cerebellar atrophy with ataxic disorders of extremities and trunk, equilibrium and gait disorders, slow voluntary movements, speech disorders, nystagmus, and oscillatory tremor of the head and trunk. Onset in adult or middle life.

Onset in middle life or later. Progressive ataxia of extremity and trunk. Dysarthria, oscillation of head and body. Mental deterioration present in some cases. Later sphincters affected. Aetiology unknown.


  • J. J. Dejerine, A. Thomas:
    L’atrophie olivo-ponto-cérébelleuse.
    Nouvelle iconographie de la Salpêtrière, Paris, 1900, 13: 330-370. 1912, 25: 223-250.
    English translatrion in David Allen Rottenberg & Fred Harvey Hochberg, editors: Neurological Classics in Modern Medicine. New York, Hafner Press, 1977. Contains full translation of 20 classic European contributions to 19th and 20th century neurology.

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