Libman-Sacks syndrome
Alternative eponyms
- Libman's endocarditis
- Libman-Sacks disease
- Kaposi-Besnier-Libman-Sacks syndrome
- Osler-Libman-Sacks syndrome
Related people
An atypical, verrucous, nonbacterial, valvular and mural endocarditis. Final stage of systemic lupus erythematodes.
Description
Final stage of systemic lupus erythematodes. An atypical, verrucous, nonbacterial, valvular and mural endocarditis. A visceral manifestation of systemic lupus erythematosus disseminatus, characterized by the presence of systolic and diastolic apical murmurs and/or chordae tendinea of sterile, verrucous lesions composed of fibrin strands. Polymorphonuclear leukocytes, lymphocytes, and histiocytes infiltrate the affected structures. The syndrome is seldom autonomous but is part of a more widespread systemic collagen disorder.
Bibliography
- E. Libman, B. Sacks:
A hitherto undescribed form of valvular and mural endocarditis.
Archives of Internal Medicine, Chicago, 1924, 33: 701-737.