- A dictionary of medical eponyms

Crosby's syndrome

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A no longer commonly used term for a hereditary, non-sherpocytic haemolytic anaemia caused by enzyme disorders, hemoglobinopathies, or defects in membrane structure. Jaundice, splenomegaly, and cholelithiasis are its main characteristics. Inheritance is autosomal recessive.


  • W. H. Crosby:
    Hereditary non spherocytic hemolytic anemia.
    Blood, New York, 1950, 5: 233-253.

  • E. Kaplan, W. W. Zuelzer:
    Familial nonpsherocytic hemolytic anemia.
    Blood, New York, 1950: 1811-1821.
  • E. Beutler:
    Hereditary nonspherocytic hemolytic anemia-pyruvate kinase deficiency and other abnormalities.
    In: W. J. Williams, E. Beutler, A. J. Erslev, M. A. Lichtman, editors: Hematology. 3rd edition, McGraw-Hill, New York, 1983, pp. 574-582.

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