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Maroteaux-Lamy syndrome II

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A familial form of idiopathic osteolysis, characterized by onset between the ages of 8 and 22 years, slow dissolution of bones of the phalanges of the hands and feet, ulcers of the fingers and soles of the feet, disappearance of bone sequestra, and loss of the digits on healing. A similar condition may be produced on exposure to vinyl chloride. Inheritance is autosomal dominant.


  • P. Maroteaux, M. Lamy:
    Acro-ostéolyse dominante.
    Archives francaises de pédiatrie, Paris, 1961, 18: 693-702.
  • D. K. Harris, W. G. Adams:
    Acro-osteolysis occurring in men engaged in the polymerization of vinyl chloride.
    British Medical Journal, London, 1967, 3: 712-714.

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