Jolly's myasthenic reaction

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A test for distinguishing between Lambert-Eton syndrome and myasthenia gravis pseudoparalytica, or Erb-Goldflam syndrome.

Description

A test for distinguishing between Lambert-Eton syndrome and myasthenia gravis pseudoparalytica, or Erb-Goldflam syndrome. It is characterized by abnormal and rapid exhaustion of the striped musculature, particularly of the eyes and face, and the proximal muscles of the extremities. Jolly’s reaction demonstrates the abnormal fatigability in repeated muscular contractions, for instance after 10-20 handshakes. See also Erb-Goldflam syndrome, under Wilhelm Heinrich Erb, German neurologist, 1840-1921

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