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Howell-Jolly bodies

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Spherical granules, 1-2 µ, seen in erythrocytes in slides of stained blood. They are thought to be nuclear particles. The bodies are seen in cases of congenital absence of the spleen; following splenectomy, in haemolytic anaemia, in percicious anaemia, in thalassaemia, and in leukaemia.


  • W. H. Howell:
    The life-history of the formed elements of the blood, especially the red blood corpuscles.
    Journal of Morphology, New York, 1890-91, 4: 57-116.
  • J. M. J. Jolly:
    Sur la formation des globules rouges des mammifères.
    Comptes rendus de la Société de Biologie, Paris, 1905, 58: 528-531. Recherches sur la formation des globules rouges des mammiféres.
    Archives d’anatomie microscopique, 1907, 9: 133-314.

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