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Hines and Brown test

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Test designed to detect latent states of hypertension. Immersion of one extremity in ice water for 1-3 minutes will normally increase the systolic and diastolic blood pressure by 15 mmHg. Failure to respond is due to a central or efferent sympathetic lesion. An excessive rise in pressure is thought to indicate latent hypertension.


  • E. A. Hines, G. Brown:
    A standard stimulus for measuring vasomotor reactions: its application in the study of hypertension.
    Proceedings of the Staff Meetings of the Mayo Clinic, Rochester, Minnesota, 1932, 7: 332-335. A standard test measuring the variability of blood pressure. Its significance as an index of the prehypertensive state.
    Annals of Internal Medicine, Philadelphia, 1933, 7: 209-217.

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