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Godtfredsen's syndrome

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Syndrome of trigeminal neuralgia, oculomotor paralysis, XIIth nerve paralysis and ophthalmoplegia, due to invasion of nasopharyngeal tumours into the base of the skull and adjacent structures, and compression of the hypoglossal nerve by enlarged retropharyngeal lymph nodes. Generally similar to the Jacod’s syndrome (retrosphenoidal syndrome).


  • E. Godtfredsen:
    Ophthalmo-neurological symptoms in connection with malignant nasopharyngeal tumors. A clinical study comprising 454 cases.
    Acta Ophthalmologica, Copenhagen, 1944; supplement 22. Ophthalmo-neurological symptoms in connection with malignant nasopharyngeal tumors.
    British Journal of Ophthalmology, London, 1947, 31: 78-100.

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