- A dictionary of medical eponyms

Foix's syndrome II

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Ophthalmoplegic disease picture originating in processes secondary to intracranial aneurysms or thrombosis of the cavernous or lateral sinuses, sometimes associated with trigeminal neuralgia. There is paralysis of the third, fourth, fifth, and sixth cranial nerves and the ophthalmic branch of the fifth cranial nerve, together with proptosis and oedema of the eyelids. There may also be trigeminal neuralgia.

The synonyms Godtfredsen’s syndrome and Foix-Jefferson syndrome are probably misnomers. Godtfredsen's syndrome, also called Foix-Jefferson syndrome, is another cavernous sinus syndrome. It is entered under Erik Godtfredsen, Danish radiologist, born 1913. Jefferson’s syndrome, or aneurysm of internal carotid artery, is entered under Sir Geoffrey Jefferson, English neurologist/neurosurgeon, 1886-1961.


  • C. Foix:
    Syndrome de la paroi externe du sinus caverneux (ophtalmoplégie unilatérale à marche rapidement progressive. Algie du territoire de l’ophtalmique). Amélioration considérable par le traitement radiothérapique.
    Revue neurologique, Paris, 1922, 38: 827-832.
  • Erik Godtfredsen:
    Ophthalmoneurological symptoms in malignant nasopharyngeal tumors.
    British Journal of Ophthalmology, London, 1947, 31: 78-100.
  • Sir Geoffrey Jefferson:
    On the saccular aneurysms of the internal carotid artery in the cavernous sinus.
    British Journal of Surgery, London, 1938-1939, 26: 267-302.

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