A rare, idiopathic, and frequently fatal form of diffuse myocarditis/viral myocarditis of unknown cause, not affecting the endocardium and pericardium. Two pathological types are recognized. The more common of the two is characterized by inflammatory interstitial reactions associated with infiltrations by leukocytes. Second, the granulomatous type, is marked by large foci containing lymphocytes, macrophages, and, sometimes, multinucleated giant-cells. The disease may occur at any age, but is most frequent in young and middle-aged men. When associated with extensive eosinophilic infiltrations, the disease is known as Rheinhard's myocarditis. Etiology uncertain. Some writers consider this not to be an independent entity.
- K. L. A. Fiedler:
Über akute interstitielle Myokarditis.
Dresden, W. Baensch, 1900.
Zentralblatt für innere Medizin, 1900, 21: 212-213.
- S. S. Abramov:
Kazuistike pervichnykh miokarditov.
Medisinskoe Obozrainie, ejemaisjachuni journal, Moscow, 1897, 48: 889-898.