Lewandowsky-Lutz dysplasia

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A generalized skin disease characterised by multiple papillomavirus-induced scaly macules anywhere on the skin and papules on the back of the hand.

Description

A generalized skin disease characterised by multiple papillomavirus-induced scaly macules anywhere on the skin and papules on the back of the hand. The disease is considered to be a precancerous form of epithelial nevi. At 20-30 years lesions which have been exposed to sunlight are likely to develop into malignity and to Morbus Bowen or Bowen’s carcinoma and then into squamous cell carcinoma. The general condition of the patient is good. Affects both sexes. Onset at any age, but usually in childhood, with more rapid development. Probably an autosomal recessive trait.

We thank Søren Nørby, Denmark, for correcting errors.

Bibliography

  • F. Lewandowsky, W. Lutz:
    Ein Fall einer bisher noch nicht beschriebener Hauterkrankung (Epidermodysplasia verruciformis).
    Archiv für Dermatologie und Syphilis, Berlin, 1922, 141: 193-202. This is the same reference as for Lewandowsky tuberculid.

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