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Crooke's cells

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Hyalinated, basophilic cells in the pituitary body found in Cushing’s syndrome, but also in exogenic administration of cortisol. They are pathogonomic for the so-called basophilic adenoma of the pituitary. Possibly degenerative secondary effects.

See also Cushing’s syndrome I, under Harvey Williams Cushing, American neurosurgeon, 1869-1939.


  • A. C. Crooke:
    A change in the basophile cells of the pituitary gland common to conditions which exhibit the syndrome attributed to basophile adenoma.
    Journal of Pathology, Chichester, 1935, 41: 339-349.

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