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Nevin-Jones disease

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Subacute encephalopathy occurring most commonly between the ages of 50 and 70 years, and characterized by blindness, motor paralysis, speech disorders, cerebellar symptoms, mental disorders, and myoclonus epilepsy. Some writers consider this and the Heidenhain syndrome to be analogous, both being variants of the Jakob-Creutzfeldt syndrome.

See also Creutzfeldt-Jakob disease, or progressive encephalopathy with spongioform degeneration of the brain, under Hans Gerhard Creutzfeldt, German neuropathologist, 1885-1964.


  • S. Nevin, W. H. Mc Menemy, D. Berhman, D. P. Jones:
    Subacute encefalopathy: a subacute form of encefalopathy attributable to vascular dysfunction (spongiform cerebral atrophy).Brain 1960, 83: 519-564.
We thank Andre Trombeta for information submitted.

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