- A dictionary of medical eponyms

Greig's syndrome II

Alternative eponyms

  • Greig's’ disease
  • Greig's ocular hypertelorism syndrome

Related people

Hereditary/familial ocular hypertelorism. Pesents as abnormal increase in distance between the eyes due to development arrest of the greater wings of the sphenoid bone.

Description

Hereditary/familial ocular hypertelorism. Presents as abnormal increase in distance between the eyes due to development arrest of the greater wings of the sphenoid bone. The vertex is high and there is a low forehead. It is sometimes associated with osteogenesis imperfecta, Sprengel deformity, and some other anomalies of the skull. Mental deficiency occasionally associated. Etiology unknown; sporadic or hereditary (autosomal dominant or X-linked). The familial form of the condition is inherited as an autosomal dominant. 1926. ?

First described by Greig in 1924. He introduced the descriptive term «hypertelorism» to designate the wide separation of the eyes. Associated malformations and mental impairment may be present. Some cases occur spontaneously, but there is a familial tendency, cases having been observed in three successive generations. It is no longer regarded as a distinct entity, but as a malformation that may occur in a variety of different syndrome.

Bibliography

  • D. M. Greig:
    Hypertelorism. A hitherto undifferentiated congenital cranio-facial deformity.
    Edinburgh Medical Journal, 1924, 31: 560-593.

What is an eponym?

An eponym is a word derived from the name of a person, whether real or fictional. A medical eponym is thus any word related to medicine, whose name is derived from a person.

What is Whonamedit?

Whonamedit.com is a biographical dictionary of medical eponyms. It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person.

Disclaimer:

Whonamedit? does not give medical advice.
This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor.