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Brissaud's infantilism

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Hypophyseal dwarfism. A congenital disease of infants and children characterized by mental deficiency, underdevelopment of the skeletal framework and dwarfism with disproportionately long trunk in relation to legs, a rounded, chubby face, deep husky voice, constipation, protuberant abdomen, thickened panniculus, rudimentary or underdeveloped sex organs, absence of permanent teeth, and lack of body hair. The condition is caused by deficiency of thyroid hormone owing to insufficiency or lack of the thyroid gland. Radiographic study of bones indicates delayed epiphyseal ossification and defective dentition.


  • E. Brissaud:
    L'infantilisme vrai.
    Nouvelle iconographie de la Salpêtrière, Paris. 1907; 20: 1-17.

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