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De Quervain's subacute struma

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Subacute, non-bacterial inflammation of the thyroid gland, often after viral infection of respiratory tract. Characterized in particular by giant cells around colloid substance and development of granuloma, hyperthermia, fever, sweating, malaise, agitation, diffuse myalgia, cephalalgia, pain in thyroid area radiating to ear or face, dysphagia, and sometimes, tachyardia. Etiology unknown. Fibrosis may appear in later stages. More common in middle aged men; onset dramatic.


  • F. de Quervain:
    Über acute, nichteitrige Thyroiditis.
    Archiv für klinische Chirurgie, Berlin, 1902, 67: 706-714.

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