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Jan van der Hoeve
Dutch ophthalmologist, born April 13, 1878, Santpoort near Velsen; died April 26, 1952, Leiden.
Associated eponyms:
Ekman-Lobstein syndrome
This rather infrequently used eponym denotes the association of brittle bones and blue sclerae, with absence of deafness. It is an inherited disorder characterised by extreme fragility of bones that begins in childhood.
Klein-Waardenburg syndrome
A hereditary congenital defect involving pigmentation, lateral displacement of the medial canthi and lacrimal points, and deafness.
Van der Hoeve's symptom
Enlargement of Mariotte’s spot in inflammation of the sinuses of the nose.
Van der Hoeve's syndrome
Osteogenesis imperfecta, or brittle bones syndrome, occurs in four types.
Biography:
After graduating from the University of Leyden, Jan van der Hoeve in 1903 obtained a doctorate at the University of Bern. He served as a military medical officer from 1905 to 1913, and subsequently was appointed as professor of ophthalmology at the University of Groningen. In 1918 he moved to the same tenure at his alma mater in Leyden. Van der Hoeve was the first to introduce the concept of phacomatoses as a group of congenital disorders with ramifications in many tissues. As a person he was described as courteous and genial.
He received an honorary degree from the University of Edinburgh and the Sir William Mackenzie medal for ophthalmic research, and in 1932 he was elected president of the Physical Section of the Royal Dutch Academy of Science.
Bibliography:
- Operationen an den Augenmuskeln.
In: Handbuch der gesamten Augenheilkund (Volume 1, Der augenärztliche Operationslehre). Berlin, 1922.
Obituary in:
- British Journal of Ophthalmology, London, 1952, 36: 399-40.
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