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Alfred Kast
German physician, born July 25, 1856, Illenau near Achern, Baden; died January 7, 1903, Nizza.
Associated eponyms:
Mafucci's syndrome
Syndrome of enchondromas (benign tumours of cartilage), associated with multiple cavernous haemangiomas.
Biography:
Alfred Kast studied medicine in Heidelberg, Freiburg, and Leipzig, graduating M.D. in Freiburg 1879. He was assistant physician under Wilhelm Heinrich Erb (1840-1921) in Heidelberg, and then worked with Julius Friedrich Cohnheim (1839-1884) in pathology in Leipzig. In 1881 he entered a position as clinical assistant to Christian Bäumler (1836-1933) in Freiburg im Breisgau, where he also worked at the physiological-chemical institute under Eugen Baumann (1846-1896).
Kast was habilitated in Freiburg in 1883 and became extraordinary professor in 1886. In 1888 he became director of the new Eppendorf Hospital in Hamburg, and in 1892 was appointed professor of internal medicine in Breslau (Wroclaw). Kast received the title of Geheimer Medicinal-Rath-Rat (privy medical counsellor).
Kast introduced phenacetin and the sulphonal group of drugs (1888), which were widely used as hypnotics before they were replaced by barbiturates. Together with Theodor Rumpel (1862-1923) he published a beautifully illustrated atlas of pathology and published widely on neurology and pharmacology.
Bibliography:
- Ueber Stoffwechselstörungen nach länger dauernder Chloroformnarkose.
Written with B. Mester. Zeitschrift für klinische Medicin, Berlin, 1891, 18: 469-479.
- Pathologisch-anatomische Tafeln nach frischen Präparaten.
With Theodor Rumpel.
Wandsbek-Hamburg, 1892-1897; translated into English.
- Ueber die Wirkung des Acetphenetidins.
Written with Oscar Heinrich Daniel Hinsberg (1857-1939).
Centralblatt für die medicinischen Wissenschaften, Berlin, 1887, 25: 145-148.
Introduction of phenacetine.
- Sulfonal, ein neues Schlafmittel.
Berliner klinische Wochenschrift, 1888, 25: 309-314. Introduction of sulphonal, previously discoveed by Eugen Baumann.We thank Rudolf Kleinert, Bad Reichenhall, Germany, for information submitted.
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