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Henry Asbury Christian

American physician, 1876-1951.




Associated eponyms:
Hand-Schüller-Christian disease
A rare disease of unknown cause in which lipids accumulate in the body and manifest as histiocytic granuloma in bone, particularly in the skull; the skin; and viscera, often with hepatosplenomegaly and lymphadenopathy.

Letterer-Siwe disease
Syndrome characterised by proliferation of nonlipid histiocytes in the viscera and bones.

Pfeifer-Weber-Christian disease
A skin disease characterized by relapsing fever and panniculitis, and development of crops of painful subcutaneous fatty nodules, resulting in atrophy of the subcutaneous fatty layer of the skin.





Biography:
Henry A. Christian was born in Virginia and graduated from Randolph-Mason College in 1895. He received his M.D. at Johns Hopkins in 1900 and worked with Frank Burr Mallory (1862-1941) at the Boston City Hospital. In 1908 he was appointed Jersey professor of theory and practice and became the first physician-in-chief to the Peter Bent Brigham Hospital, retiring in 1939. He reported a typical example of the disorder in 1919. He was an outstanding teacher and clinician who wrote a number of texts and guided many young people into academic medicine.


Bibliography:
  • Defects in membranous bones, exophtalmos, and diabetes insipidus; an unusual syndrome of dyspituitarism.
    In: Contributions to medical and biological research, dedicated to Sir William Osler. New York, P. B. Hoeber, 1919, 1: 390-401.
    Medical Clinics of North America, Philadelphia, PA., 1920; 3: 849-871.
    Hand-Schüller-Christian disease.

  • Relapsing febrile nodular nonsuppurative panniculitis.
    Archives of Internal Medicine, Chicago, 1928, 42: 338-351.
    Pfeifer-Weber-Christian disease



 
 

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