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Alfred Hand Jr.
American paediatrician, born February 7, 1868, Scranton, Pennsylvania; died 1949.
Associated eponyms:
Hand-Schüller-Christian disease
A rare disease of unknown cause in which lipids accumulate in the body and manifest as histiocytic granuloma in bone, particularly in the skull; the skin; and viscera, often with hepatosplenomegaly and lymphadenopathy.

Letterer-Siwe disease
Syndrome characterised by proliferation of nonlipid histiocytes in the viscera and bones.

Biography:
Alfred Hand Jr studied at the University of Pennsylvania, graduating there in 1892. He spent his time as intern at the Children’s Hospital and the German Hospital. From 1902 to 1930 he was physician at the Children’s Hospital of Philadelphia, 1914-1928 paediatrician at the Methodist Hospital, and from 1904 also physician to the Children’s Hospital of the Mary Drexel Home.
1896-1899 demonstrator of pathological histology at the University of Pennsylvania, from 1920 he taught paediatrics at the Graduate Medical School in Philadelphia. He was very active in scientific work in the field of paediatrics.
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