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Otto von Bollinger

Born  1843
Died  1909

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German pathologist, Born April 2, 1843, Altenkirchen, Rheinpfalz;Died August 13, 1909, Munich.

Biography of Otto von Bollinger

Otto Bollinger studied in Munich, Vienna and Berlin, where he obtained his doctorate in 1868. He subsequently worked as an assistant to professor Ludwig von Buhl (1816-1880). He was habilitated in 1870 and taught at the Tierärtzliche Hochschule in Zürich. In 1874 he was called to the position of professor extraordinary at the Tierarzneischule in Munich. In 1880 he succeeded Buhl as professor of general pathology and pathological anatomy at the University of Munich.

In 1877, Bollinger described the etiologic agent of bovine actinomycosis ("lumpy jaw"), which was soon afterwards called actinomyces bovis.

In 1891 Bollinger provided an early description of a delayed traumatic apoplexy he called traumatische Spät-Apoplexie. Today this condition is called delayed traumatic intracerebral hematoma or (DTICH). His research was based on four patients who suffered a head injury, in which death occurred days to weeks later from an apoplectic event.

Bollinger was known for his studies of rabies and hydrophobia in the days before the discovery of an anti-rabies vaccine. From a series of collected statistics states that of patients bitten by dogs undoubtedly rabid 47% died, the rate being 33% in those whose wounds had been cauterized and 83% when there had been no local treatment. In England in 1895, 668 dogs, besides other animals, were killed and certified to be rabid, and the deaths from hydrophobia were twenty.

Bollinger is credited with describing the inclusion bodies found in tissue cells in fowlpox. These bodies contain the fowlpox virus, and are now referred to as Bollinger bodies. Another eponymous term named after him are Bollinger granules, which are small yellowish-white granules that cluster, contain micrococci, and are seen in the granulation tissue of botryomycosis.

Otto Bollinger was co-founder and editor of the journal Deutsche Zeitschrift für Tiermedizin und vergleichende Pathologie.

Bibliography

  • Zur Pathologischen Anatomie der Acuten Leberatrophie und der Phosphorvergiftung.
    Doctoral thesis, University of Munchen,
  • Mycosis der Lunge beim Pferde. Botriomycosis first described.
    Archiv für pathologische Anatomie und Physiologie und für klinische Medicin, 1870, 49: 583-586.
    Botromycosis was originally discovered by Otto Bollinger, and its name was coined by Sebastiano Rivolta (1832-1893) in 1884. The name refers to its grape-like granules. The bacterial origin of the infection was discovered in 1919.
  • Beiträge zur vergleichenden Pathologie und pathologischen Anatomie der Hausthiere. Die Kolik der Pferde und das Wurmaneurysma der Eingeweidearterien. Eine pathologisch-anatomische und klinische Untersuchung. Mit 19 Holzschnitten.
    München, 1870.
    Heft 2: Zur Pathologie des Milzbrandes. München 1872.
  • Infectionen durch thierische Gifte. Zoonosen.
    In: Hugo Wilhelm von Ziemssen (1829-1902), et al: Handbuch der speciellen Pathologie und Therapie. 4 volumes, Leipzig : F. C,. Vogel.
  • Infectionen durch thierische Gifte. Milzbrand.
    In: Hugo Wilhelm von Ziemssen (1829-1902), et al: Handbuch der speciellen Pathologie und Therapie. 4 volumes, Leipzig : F. C,. Vogel. Volume 3: 1875: 447-490.
  • Handbuch der Syphilis, der Invasionskrankheiten und der Zoonosen.
    Chr. Bäumler, Arnold Heller (1840-1913) and O. Bollinger.
    2. Auflage., Leipzig : F. C. Vogel, 1876.
  • Infectionen durch thierische Gifte. Invasionskrankheiten.
    Chr. Bäumler, Arnold Heller (1840-1913) and O. Bollinger.
    In: Hugo Wilhelm von Ziemssen (1829-1902), et al: Handbuch der speciellen Pathologie und Therapie. 4 volumes, Leipzig : F. C,. Vogel. 1876.
  • Ueber Menschen- und Thierpocken, über den Urpsrung der Kuhpocken und über intrauterine Vaccination.
    [Volkmanns] Sammlung klinischer Vorträge, Leipzig, 1877, 116. 40 pages.
  • Ueber eine neue Pilzkrankheit beim Rinde.
    Centralblatt für die Medicinischen Wissenschaften, Berlin, 1877, 15: 481-485.
    First effective description of Actinomyces bovis.
  • er animale Vaccination.Bericht über eine im Auftrag des Kgl. Bayer. Staatsministeriums des Innern für Kirchen- und Schul-Angelegenheiten zum Besuche der animalen Impf-Anstalten in Belgien, Holland und Hamburg unternommenen Reise.
    Leipzig : Vogel, 1879. 169pages.
  • Über eine neue Wild- und Rinderseuche - welche im Sommer 1878 in der Umgebung von München beobachtet wurde. 1878.
  • Ueber Zwerg- und Riesenwuchs. Vortrag in München.
    Sammlung gemeinverständlicher wissenschaftlicher Vorträge. Heft 455, 1884.
  • Über idiopathische Hezvergrösserung. München 1893.
  • Über traumatische spät-apoplexie; ein Beitrag zur Lehre von der Hirnerschütterung.
    In: Rudolf Virchow, editor. Internationale Beitrage zur Wissenschaftlichen Medizin. Berlin: A. Hirschwald, 1891.
  • Die Wuthkrankheit. In: Handbuch der chronischen Infectionskrankheiten, by Chr. Bäumler, Arnold Heller (1840-1913) and O. Bollinger. Third volume of: Hugo Wilhelm von Ziemssen (1829-1902), et al: Handbuch der speciellen Pathologie und Therapie. Leipzig : F. C,. Vogel, 1874. 629 pages.
    Bollinger described the presence of Actinomyces bovis in cattle. Shortly afterwards, James Israel discovered Actinomyces israelii in humans.
  • Zur Prophylaxis der Wuthkrankheit.
    Münchener medizinische Wochenschrift, 1896, 43 (12).

  • Atlas und Grundriss der pathologischen Anatomie : nach Originalien von A. Smithson. With Joseph Bauer (1845-1912).
    2 volumes, München, J. F. Lehmann, 1896-1897. 2nd edition 1901.
    Lehmann's Medicinische Hand-Atlanten, 11+12. Translated into English and French.
    Atlas and essentials of pathological anatomy (Wood's medical hand atlases) . Published by William Wsood, 1898. Biographical etc:
  • Isidor Fischer (1869-1943), publisher:
    Biographisches Lexikon der hervorragenden Ärzte der letzten fünfzig Jahre.
    Berlin – Wien, Urban & Schwarzenberg, 1932.
  • Jeremy M. Norman, editor:
    Morton’s Medical Bibliography. An annotated Check-list of Texts Illustrating the History of Medicine (Garrison and Morton).
    Fifth edition. Scolar Press, 1991.
  • Wikipedia.

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