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Mary Whittaker

English biochemist.




Associated eponyms:
Harris-Whittaker syndrome
A particular familial variant of pseudocholesterinase.





Biography:
Mary Whittaker worked in the Department of Biochemistry, The London Hospital Medical College, and was also affiliated with St. Bartholomew's Hospital, London.


Bibliography:
  • F. L. Warren, M. Whittaker:
    Molecular structure of glycogens isolated from the livers of foetal animals.
    The Biochemical Journal, London, June 1959, 72 (2): 288-293.

  • H. Harris, M. Whittaker:
    Differential response of human serum cholinesterase types to an inhibitor in potato. Nature, London, June 27, 1959, 183: 1808-1809.

  • H. Lehmann, E. Silk, H. Harris, M. Whittaker:
    A new pseudocholinesterase phenotype?
    Acta genetica et statistica medica, Basel, 1960, 10: 241-246.

  • H. Harris, M. Whittaker, H. Lehmann, E. Silk:
    The pseudocholinesterase variants. Esterase levels and dibucaine numbers in families selected through suxamethonium sensitive individuals.
    Acta genetica et statistica medica, Basel, 1960, 10: 1-16.

  • H. Harris, M. Whittaker:
    Differential inhibition of human serum cholinesterase with fluoride: recognition of two new phenotypes. Nature, London, July 1961, 191: 496-498.

  • H. Harris, M. Whittaker:
    The serum cholinesterase variants. A study of twenty-two families selected via the 'intermediate' phenotype.
    Annals of Human Genetics, July 1962, 26: 59-72.

  • H. Harris, M. Whittaker:
    Differential inhibition of the serum cholinesterase phenotypes by solanine and solanidine. Annals of Human Genetics, July 1962, 26: 73-76.

  • H. Harris, D. A. Hopkinson, E. B. Robsopn, M. Whittaker:
    Genetical studies on a new variant of serum cholinesterase detected by electrophoresis.
    Annals of Human Genetics, June 1963, 26: 359-382.

  • H. Harris, M. Whittaker:
    Differential inhibition of "usual" and "atypical" serum cholinesterase by NACL and NAF. Annals of Human Genetics, August 1963, 27: 53-58.

  • M. Whittaker:
    The pseudocholinesterase variants: esterase levels and increased resistance to fluoride. Acta genetica et statistica medica, Basel. 1964, 14: 281-285.

  • J. C. Thompson, M. Whittaker:
    Pseudocholinesterase activity in thyroid disease.
    Journal of Clinical Pathology, London, November 1965, 18 (6): 811-812.

  • J. C. Thompson, M. Whittaker:
    A study of the pseudocholinesterase in 78 cases of apnoea following suxamethonium. Acta genetica et statistica medica, Basel, 1966, 16 (3): 209-222.

  • M. Whittaker:
    The pseudocholinesterase variants. Differentiation by means of sodium chloride.
    Acta genetica et statistica medica, Basel, 1968, 18 (6): 556-562.

  • M. Whittaker:
    The frequency of the fluoride resistant gene in a population of British students.
    Acta genetica et statistica medica, Basel, 1968, 18 (6): 563-566.

  • M. Whittaker:
    Frequency of atypical pseudocholinesterase in groups of individuals of different ethnographical origin.
    Acta genetica et statistica medica, Basel, 1968, 18 (6): 567-572.

  • D. A. Birks, V. J. Prior, E. Silk, M. Whittaker:
    Echothiophate iodide treatment of glaucoma in pregnancy.
    Archives of Ophthalmology, Chicago, March 1968, 79 (3): 283-285.

  • M. Whittaker, M. D. Vickers:
    Suxamethonium apnoea.
    British Journal of Anaesthesia, London, May 1968, 40 (5): 393.

  • M. Whittaker:
    An additional pseudocholinesterase phenotype occurring in suxamethonium apnoea.
    British Journal of Anaesthesia, London, August 1968, 40 (8): 579-582.

  • M. Whittaker:
    Serum haptoglobin in the nephrotic syndrome. Other renal diseases and rheumatoid arthritis. American Journal of Clinical Pathology, Philadelphia, October 1968, 50 (4): 454-458.

  • M. Whittaker, M. D. Vickers:
    Suxamethonium apnoea.
    British Medical Journal, London, October 26, 1968, 4 (5625): 254.

  • M. Whittaker, C. A. Hardisty:
    Properties of "usual" and "atypical" serum cholinesterases using o-nitrophenyl butyrate as substrate.
    Clinical Chemistry, Baltimore, June 1969, 15 (6): 445-451.

  • M. Whittaker:
    The serum cholinesterase variants. Differentiation by means of formaldehyde.
    Clinica chimica acta, Amsterdam, October 1969, 26 (1): 141-145.

  • M. Whittaker:
    Genetic aspects of succinylcholine sensitivity.
    Anesthesiology, Philadelphia, February 1970, 32 (2): 143-150. Review.

  • M. Whittaker:
    The effect in vitro of thyroxine, glucagon, thyrotrophin and antithyroid drugs on 'usual' and 'atypical' human plasma cholinesterase.
    The Journal of Endocrinology, Bristol, June 1970, 47 (2): 177-182.

  • M. Whittaker, M. D. Vickers:
    Initial experiences with the Cholinesterase Research Unit.
    British Journal of Anaesthesia, London, November 1970, 42 (11): 1016-1020.

  • G. G. Bird, G. A. Bunch, C. B. Croft, D. C. Hoffmann, C. S. Humphrey, J. R. Rhind, J. L. Rosenberg, M. Whittaker, A. R. Wilkinson, R. Hall:
    Topical noxythiolin antisepsis. Report of a controlled trial.
    The British Journal of Surgery, Bristol, June 1971, 58 (6): 447-448.

  • M. Whittaker, A. R. Charlier, S. Ramaswamy:
    Changes in plasma cholinesterase isoenzymes due to oral contraceptives.
    Journal of Reproduction and Fertility, Cambridge UK, September 1971, 26 (3): 373-375.

  • J. L. Laity, M. Whittaker:
    Neuromuscular actions of lignocaine and prilocaine.
    British Journal of Pharmacology, London, October 1971, 43 (2): 431P-432P.

  • M. Whittaker, M. Berry.
    The pseudocholinesterase variants. A family segregating for two homozygotes with the fluoride resistant gene.
    Human Heredity, Basel, 1972, 22 (3): 243-248.

  • M. Whittaker, A. R. Charlier:
    The effect of phospholipase A on human erythrocyte acetylcholinesterase.
    FEBS Letters, Amsterdam, May 1972, 22 (3): 283-286.

  • M. Whittaker, A. R. Charlier:
    The effects of lipases and proteases on "usual" and "atypical" serum cholinesterase.
    Enzymologia, June 30, 1972, 42 (6): 423-430.

  • P. Jackson, M. Whittaker:
    Evidence for an abnormality in the erythrocyte membranes of patients having paroxysmal nocturnal haemoglobinuria and aplastic anemia.
    Clinica chimica acta, Amsterdam, October 1972, 41: 299-304.

  • P. Jackson, M. Whittaker:
    Some characteristics of acetylcholinesterase extracted from human erythrocytes by three different detergents.
    Enzymologia, Den Haag, December 31, 1972, 43 (6): 359-671.

  • E. A. Benson, G. J. Brown, M. Whittaker:
    Prevention of wound infection in acute appendicitis.
    The Lancet, London, August 11, 1973, 2 (7824): 322.

  • M. Whittaker, R. V. Kerr:
    Successful treatment of ileofemoral venous thrombosis following cardiac catheterization.
    Thorax, London, November 1973, 28 (6): 794-796.

  • N. V. Addison, F. A. Brear, K. Budd, M. Whittaker:
    Epidural analgesia following cholecystectomy.
    The British Journal of Surgery, Bristol, October 1974, 61 (10): 850-852.

  • M. Whittaker, R. Reys:
    Plasma cholinesterase studies on south-eastern Bantu of Mozambique.
    Human Heredity, Basel, 1975, 25 (4): 296-301.

  • M. Whittaker, C. K. Anderson, P. B. Clark:
    Sarcoidosis of the penis treated by radiotherapy.
    British Journal of Urology, London, June 1975, 47 (3): 325-330.

  • M. Berry, M. Whittaker:
    Incidence of suxamethonium apnoea in patients undergoing E.C.T.
    British Journal of Anaesthesia, London, November 1975, 47 (11): 1195-1197.

  • M. Whittaker, R. F. Lowe, B. P. Ellis:
    Serum cholinesterase variants in African leprosy patients resident in Rhodesia.
    Human Heredity, Basel, 1976, 26 (5): 372-379.

  • M. Whittaker, R. F. Lowe:
    The cholinesterase variants found in some African tribes living in Rhodesia.
    Human Heredity, Basel, 1976, 26 (5): 380-393.

  • M. Whittaker, J. C. Goligher:
    The prognosis after surgical treatment for carcinoma of the rectum.
    The British Journal of Surgery, Bristol, May 1976, 63 (5): 384-388.

  • M. Whittaker, J. C. Goligher:
    A comparison of the results of extraperitoneal and intraperitoneal techniques for construction of terminal iliac colostomies.
    Diseases of the Colon & Rectum, New York, May-June 1976, 19 (4): 342-344.

  • P. W. Lee, M. Whittaker, T. J. Hall:
    Spontaneous rupture of the spleen in infectious mononucleosis.
    Postgraduate Medical Journal, London, November 1976, 52 (613): 725-726.

  • M. Whittaker, M. Berry:
    Plasma cholinesterase polymorphism in Down's syndrome.
    Human Heredity, Basel, 1977, 27 (1): 52-58.

  • M. Whittaker, R. Spencer:
    Plasma cholinesterase variants in patients having lithium therapy.
    Clinica chimica acta, Amsterdam, March 15, 1977, 75 (3): 421-425.

  • M. Whittaker, M. Berry:
    The plasma cholinesterase variants in mentally ill patients.
    The British Journal of Psychiatry, London, April 1977, 130: 397-404.

  • M. Whittaker, R. Spencer, J. Searle:
    Plasma cholinesterase and malignant hyperthermia.
    British Journal of Anaesthesia, London, April 1977, 49 (4): 393.

  • A. S. Fairhurst, M. Whittaker, R. Wiener:
    vSmooth muscle in an animal model of myotonic dystrophy.
    Experimental Neurology, April 1978, 59 (2): 286-295.

  • A. B. Jenkins, M. Whittaker, P. J. Schofield:
    The starvation induced increase in muscle protein degradation is non-lysosomal in origin.
    Biochemical and Biophysical Research Communications, New York, February 28, 1979, 86 (4): 1014-1019.

  • E. Silk, J. King, M. Whittaker:
    Scientific Review No. 5. Assay of cholinesterase in clinical chemistry.
    Annals of Clinical Biochemistry, London, March 1979, 16 (2): 57-75.

  • M. Whittaker:
    Plasma cholinesterase variants and the anaesthetist.
    Anaesthesia, February 1980, 35 (2): 174-197. Review.

  • R. Melvoll, J. Stovner, M. Whittaker:
    Suxamethonium-induced jaw stiffness and myalgia associated with atypical cholinesterase: case report.
    The Canadian Anaesthetists' Society Journal, Toronto, May 1980, 27 (3): 283-285.

  • P. Clarke, M. Whittaker:
    Traumatic aneurysm of the internal carotid artery and rupture of the duodenum following seat belt injury.
    Injury, September 1980, 12 (2): 158-160.

  • T. S. Brown, M. Whittaker:
    Struma-reticulosa and reticulum-cell sarcoma of the stomach and oesophagus.
    The Practitioner, London, October 1980, 224 (1348): 1086-1087.

  • M. Whittaker, J. Britten:
    Inhibition of the plasma cholinesterase variants by pancuronium bromide and some of its analogues.
    Clinica chimica acta, Amsterdam, November 20, 1980, 108 (1): 89-94.

  • S. S. Brown, W. Kalow, Pilz W, M. Whittaker, C. L. Woronick:
    The plasma cholinesteerases: a new perspective.
    Advances in Clinical Chemistry, 1981, 22: 1-123. Review.

  • M. Whittaker, J. Britten:
    A comparison of some methods of phenotyping the plasma cholinesterase variants using benzoylcholine as substrate.
    Annals of Clinical Biochemistry, London, January 1981, 18 (Pt 1): 9-14.

  • M. Whittaker, J. Britten.
    Differential inhibition of plasma cholinesterase variants using the dibutyrate analogue of pancuronium bromide.
    Human Heredity, Basel, 1981, 31 (4): 242-247.

  • M. Whittaker, J. Britten:
    Malignant hyperthermia and the fluoride-resistant gene.
    British Journal of Anaesthesia, London March 1981, 53 (3): 241-244.

  • M. Whittaker, J. Britten, R. J. Wicks:
    Inhibition of the plasma cholinesterase variants by propranolol.
    British Journal of Anaesthesia, London, May 1981, 53 (5): 511-516.

  • P. D. Morrison, M. Whittaker:
    A case of Hodgkin's disease complicating Crohn's disease.
    Clinical Oncology, London, 1982, 8 (3): 271-272.

  • M. Whittaker, R. J. Wicks, J. Britten:
    Studies on the inhibition by propranolol of some human erythrocyte membrane enzymes and plasma cholinesterase.
    Clinica chimica acta, Amsterdam, February 26, 1982, 119 (1-2): 107-114.

  • D. Browning, M. Whittaker, R. McInerney:
    Doctors and nuclear war; prevention of nuclear war; nuclear war--more questions.
    The Medical Journal of Australia, Sydney, November 27, 1982, 2 (11): 506-507.

  • M. Whittaker:
    Prevention of nuclear war.
    The Medical Journal of Australia, Sydney, November 27, 1982, 2 (11): 507.

  • T. R. Hardwell, J. Braven, S. Shaw, M. Whittaker:
    Phosphoribosyl pyrophosphate synthetase and glutathione reductase in erythrocytes from hyperuricaemic and gout patients.
    Clinica chimica acta, Amsterdam, December 23, 1982, 126 (3): 217-226.

  • M. Whittaker, J. S. Crawford:
    Postoperative ileus, pregnancy-related cholinesterase deficiency and suxamethonium after-pains. A case report.
    British Journal of Anaesthesia, London, June 1983, 55 (6): 581-584.

  • Colin F. Simpson and Mary Whittaker, editors:
    Electrophoretic techniques. London : Academic, 1983.

  • A. Ferguson, M. Whittaker, J. Britten, B. W. Perriss:
    Suxamethonium apnoea associated with pregnancy and liver dysfunction in a treated cretin. Anaesthesia, Oxford UK, June 1983, 38(6):567-71.

  • T. R. Hardwell, G. Manley, J. Braven, M. Whittaker:
    The binding of urate to plasma proteins determined by four different techniques.
    Clinica chimica acta, Amsterdam, September 15, 1983, 133 (1): 75-83.

  • M. Whittaker, J. Britten, P. J. Dawson:
    Comparison of a commercially available assay system with two reference methods for the determination of plasma cholinesterase variants.
    Clinical Chemistry, Baltimore, October 1983, 29(10): 1746-1751.

  • J. M. Turner, R. A. Hall, M. Whittaker, L. J. Kricka:
    Effects of storage and repeated freezing and thawing on plasma cholinesterase activity. Annals of Clinical Biochemistry, London, September 1984, 21 (Pt 5):363-365.

  • J. Braven, T. R. Hardwell, R. Seddon, M. Whittaker:
    A spectrophotometric assay of phosphoribosyl pyrophosphate synthetase.
    Annals of Clinical Biochemistry, London, September 1984, 21 (Pt 5): 366-371.

  • M. Whittaker, J. Britten:
    Plasma cholinesterase variants. Family studies of the E1k gene.
    Human Heredity, Basel, 1985, 35 (6): 364-368.

  • M. Whittaker, P. M. Sokolove, R. G. Thurman, F. C. Kauffman:
    Stimulation of 3-benzo[a]pyrenyl glucuronide hydrolysis by calcium activation of microsomal beta-glucuronidase.
    Cancer Letters, Amsterdam, March 1985, 26 (2): 145-152.

  • J. M. Turner, R. A. Hall, M. Whittaker, R. L. Holder, L. J. Kricka:
    Application of stepwise discriminant analysis in the phenotyping of plasma cholinesterase variants.
    Annals of Clinical Biochemistry, London, March 1985, 22 (Pt 2): 175-178.

  • M. Whittaker:
    Key Issues in Human Genetics.
    Monographs in Human Genetics: Cholinesterase: Volume 11. Karger, 1986. 136 pages.

  • N. Robson, I. Robertson, M. Whittaker:
    Plasma cholinesterase changes during the puerperium.
    Anaesthesia, Oxford UK, March 1986, 41 (3): 243-249.

  • J. Braven, T. R. Hardwell, P. Hickling, M. Whittaker:
    Effect of treatment on erythrocyte phosphoribosyl pyrophosphate synthetase and glutathione reductase activity in patients with primary gout.
    Annals of the Rheumatic Diseases, London, November 1986, 45 (11): 941-944.

  • M. Whittaker, J. Britten:
    E1h, a new allele at cholinesterase locus 1.
    Human Heredity, Basel, 1987, 37 (1): 54-58.

  • M. Whittaker, F. Taylor, E. F. Battersby:
    Recognition of the E1kE1f cholinesterase genotype in a family segregating three rare genes, E1k, E1f and E1a.
    Human Heredity, Basel, 1987, 37(2):82-85.

  • M. Whittaker, J. Britten:
    Phenotyping of individuals sensitive to suxamethonium. The Cholinesterase Research Unit at the Royal Postgraduate Medical School.
    British Journal of Anaesthesia, London, August 1987, 59 (8): 1052-1055.

  • M. Whittaker, J. Britten:
    Analysis of suxamethonium sensitivity following termination of pregnancy.
    British Journal of Anaesthesia, London, September 1987, 59 (9): 1157-1159.

  • J. Anglister, M. W. Bond, T. Frey, Leahy D, M. Levitt, H. M. McConnell, G. S. Rule, J. Tomasello, M. Whittaker:
    Contribution of tryptophan residues to the combining site of a monoclonal anti dinitrophenyl spin-label antibody.
    Biochemistry, Washington, September 22, 1987, 26 (19): 6058-6064.

  • M. Whittaker, J. S. Crawford, M. Lewis:
    Some observations of levels of plasma cholinesterase activity within an obstetric population.
    Anaesthesia, Oxford UK, January 1988, 43 (1): 42-45.

  • M. Whittaker, J. Britten, A. B. Vyas, T. C. Hayes:
    Family studies of the E1kE1s genotype for plasma cholinesterase.
    Human Heredity, Basel, 1988, 38 (4): 228-232.

  • M. Whittaker, J. Britten:
    Recognition of two new phenotypes segregating the E1k allele for plasma cholinesterase.
    Human Heredity, Basel, 1988, 38 (4): 233-239.

  • M. Whittaker, J. Britten:
    Segregation of the E1j gene for plasma cholinesterase in family studies.
    Human Heredity, Basel, 1989, 39 (1): 1-6.

  • J. Braven, N. Ansari, D. P. Figgitt, A. Fisher, C. Luders, P. Hickling, M. Whittaker:
    A comparison of glutathione reductase and glutathione peroxidase activities in patients with rheumatoid arthritis and healthy adults.
    British Journal of Rheumatology, Oxford UK, June 1989, 28 (3): 212-215.

  • M. Whittaker, M. Berry, J. Britten:
    Inheritance of low plasma cholinesterase activity in two families with a history of suxamethonium sensitivity.
    Anaesthesia, Oxford UK, June 1989, 44 (6): 480-482.

  • J. Eng, S. Sabanathan, M. Whittaker:
    Primary anorectal malignant melanoma. A case report.
    Acta chirurgica Scandinavica, Stockholm, June-July, 1989, 155 (6-7): 357- 359.

  • I. Anundi, F. C. Kauffman, J. M. te Koppele, H. Yamanaka, M. Whittaker, J. A. Popp, R. G. Thurman:
    Adenine nucleotides and carbohydrates in subpopulations of hepatic nodules with normal and compromised microcirculation.
    Cancer Research, June 15, 1989, 49 (12): 3282-3286.

  • M. Whittaker, K. Fomcar, T. Keith, B. McAneny:
    Simultaneous nodular lymphocyte predominance Hodgkin's disease (N-LPHD) and large-cell lymphoma (LCL). The American Journal of Surgical Pathology, New York, August 1989, Aug, 13 (8): 715-716.

  • F. C. Kauffman, M. Whittaker, M. Z. Badr, R. G. Thurman:
    Effect of epinephrine on glycogen phosphorylase-alpha in various preparations of rat liver.
    Comparative Biochemistry and Physiology. B, 1990, 96 (1): 113-118.

  • M. Whittaker, J. Jones, J. Braven:
    Heterogeneity of the silent gene for plasma cholinesterase. Immunological studies.
    Human Heredity, Basel, 1990, 40 (3): 153-158.

  • M. Whittaker, J. Britten:
    Recognition of the Ek1Ek1 homozygote for plasma cholinesterase.
    Human Heredity, Basel, 1990, 40 (4): 247-249.

  • F. C. Kauffman, L. H. Davis, M. Whittaker:
    Activation of glycogen phosphorylase in rat pheochromocytoma PC12 cells and isolated hepatocytes by organophosphates.
    Biochemical Pharmacology, January 15, 1990, 39 (2): 347-354.

  • M. Z. Badr, J. A. Handler, M. Whittaker, F. C. Kauffman, R. G. Thurman:
    Interactions between plasticizers and fatty acid metabolism in the perfused rat liver and in vivo. Inhibition of ketogenesis by 2-ethylhexanol.
    Biochemical Pharmacology, February 15, 1990, 39 (4): 715-721.

  • C. L. Willman, B. B. Griffith, M. Whittaker:
    Molecular genetic approaches for the diagnosis of clonality in lymphoid neoplasms.
    Clinics in Laboratory Medicine, Philadelphia, March 1990, 10 (1): 119-149. Review.

  • M. A. Castle, R. Likwa, M. Whittaker:
    Observations on abortion in Zambia.
    Studies in Family Planning, New York, July-August 1990, 21 (4): 231-235.

  • B. L. Taylor, M. Whittaker, V. Van Heerden, J. Britten:
    Cholinesterase deficiency and the Churg-Strauss syndrome.
    Anaesthesia, Oxford UK, August 1990, 45 (8): 649-652.

  • M. Whittaker:
    Bequeath, bury or burn?
    Nursing Times, London, October 3-9, 1990, 86 (40): 34-37.

  • R. A. Milligan, M. Whittaker, D. Safer:
    Molecular structure of F-actin and location of surface binding sites.
    Nature, London, November 15, 1990, 348 (6298): 217-221.

  • M. Whittaker, J. W. Jones, J. Braven:
    Immunological studies of families segregating the silent gene for plasma cholinesterase. Human Heredity, Basel, 1991, 41 (2): 77-83.

  • M. A. Koenig, M. Whittaker:
    Increasing the application of operations research findings in public sector family planning programs: lessons from the ICDDR,B Extension Project.
    Progress in Clinical and Biological Research, New York, 1991, 371: 451-60.

  • F. C. Kauffman, M. Whittaker, I. Anundi, R. G. Thurman:
    Futile cycling of a sulfate conjugate by isolated hepatocytes.
    Molecular Pharmacology, New York, March 1991, 39 (3): 414-420.

  • J. Hangaard, M. Whittaker, A. G. Loft, B. Nørgaard-Pedersen:
    Quantification and phenotyping of serum cholinesterase by enzyme antigen immunoassay: methodological aspects and clinical applicability.
    The Scandinavian Journal of Clinical & Laboratory Investigation, Oslo, June 1991, 51 (4): 349-358.

  • M. Whittaker, J. W. Jones, J. Braven:
    Immunological studies of plasma cholinesterase during pregnancy and the puerperium.
    Clinica chimica acta, Amsterdam, July 15, 1991, 199 (3): 223-230.

  • J. W. Jones, M. Whittaker, J. Braven:
    Immunological assay of erythrocyte acetylcholinesterase.
    Clinica chimica acta, Amsterdam, August 30, 1991, 200 (2-3): 175-181.








 
 

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