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Frank Spiller Locke
English physiologist, 1871-1949. London.
Associated eponyms:
Cabot-Locke murmur
An early diastolic murmur like that of aortic insufficiency, heard best at the left lower central border in severe anaemia.
Locke-Ringer solution
An isotonic electrolytic infusion solution.
Ringer's solution
A solution used in physiological experiments. It contains sodium, potassium, calcium, and magnesium chlorides; sodium bicarbonate, dextrose, and water.
Tyrode's solution
Salt solution which is a modified Locke solution, used in physiological experiments, tissue cultures and tissue preservation, and to irrigate the peritoneal cavity.
Biography:
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