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Lewis B. Holmes
American paediatrician, geneticist and teratologist.
Associated eponyms:
Greig's syndrome I
A syndrome affecting the development of the skull, face, and limbs
Hootnick-Holmes syndrome
A familial syndrome of polysyndactyly, craniofacial anomalies, mental retardation, etc.
Biography:
Lewis B. Holmes is an internationally respected expert in genetics and teratology. He graduated in medicine from Duke University Medical Center, Durham, North Carolina, in 1963. He is professor of paediatrics at Harvard Medical School and chief of the Genetics and Teratology Unit, Pediatric Services, Massachusetts General Hospital, Boston. The Genetics and Teratology Unit is maintaining the AED (Antieleptic Drug) Pregnancy Registry, the first North American registry for pregnant women who are taking anti-epileptic drugs. Holmes is the editor-in-chief of the journal Teratology.
His son, Lewis B. Holmes Jr. graduated in medicine from the University of Massachusetts in 1993.
Bibliography:
- John S. Reif, Maureen C. Hatch, Michael Bracken, Lewis B. Holmes, Bernard A. Schwetz, and Philip C. Singer:
Reproductive and Developmental Effects of Disinfection By-products in Drinking Water.
Environmental Health Perspectives, 1996, Volume 104, Number 10 (October).
- M. H Owen, L. B. Holmes:
Restricted pattern of expression of tibia hypoplasia and reduced number of vertebrae produced by Dominant hemimelia.
Teratology, New York, 1998, 57(2): 107.
- M. H Owen, L. B. Holmes:
Stage and dose dependent effects of all-trans retinoic acid on expression of Dominant hemimelia in mice.
Teratology, New York, 1998, 57(2): 108.
- Taosheng Huang, Ellen Elias, John B Mulliken, Daniel J Kirse and Lewis B Holmes:
A new syndrome: cardiac defects, Laryngeal anomalies, preaxial polydactyly, and colonic aganglionosis in sibs.
Genetics in Medicine, 1998.
- B. J. Morin, M. H. Owen, G. V. Raumamurthy, L. B. Holmes:
Pattern of skeletal malformations produced by Dominant hemimelia (Dh).
Teratology, In Press - December, 1999.
- Edward J. Lammer and Lewis B. Holmes:
Human Teratogens.
In: Congenital Anomalies of the Ear, Nose, and Throat. Edited by Ted L. Tewfik, and Vazken M. Der Kaloustian. 1997.
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