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Knud Haraldsen Krabbe
Danish neurologist, born March 3, 1885, Frederiksberg; died 1965.
Associated eponyms:
Alpers' disease
A rare degenerative disease of the brain, predominantly involving the grey matter.
Krabbe's disease
An inborn neurodegenerative disorder of infancy due to the accumulation of galactocerebroside in the tissues.
Krabbe's syndrome II
Historical term for congenital myopathies with generalised atrophy of the musculature.
Sturge-Weber syndrome
A congenital disorder involving the brain, skin and eyes.
Biography:
Knud (Haraldsen) Krabbe is one of the major figures in Nordic neurology. He was an exceptionally gifted researcher, publishing his first scientific paper, on a biological topic, at the age of ten years. He spoke Greek at the age of three years. Born into a medical family, Krabbe in initially intended to study zoology, but changed his mind and entered the medical school of the University of Copenhagen. He was professor of neurology and chief of the neurological service of the Kommunehospitalet in Copenhagen from 1933 to 1955.Krabbe was interested in comparative anatomy and studied the morphogenesis of the brain of submammalian species. He championed the theory that many cerebral haemorrhages were secondary to vascular malformation. Despite being affected by Parkinsonism, Krabbe continued to write articles up to his death at the age of 80 years.
Knud Krabbe founded the journal Acta psychiatrica et neurologica scandinavica in 1926 and was its editor for almost 30 years. In 1927 he published a textbook of neurology.
Obituary: Revue neurologique, Paris, 1965, 113: 40.
Bibliography:
- Morphogenesis of the Brain. 1927.
A monumental 8 volume work on comparative neuroanatomy.
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