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Wilhelm Siegmund Frei
German dermatologist, born September 5, 1885, Neustadt, Ober-Schlesien; died 1943.
Associated eponyms:
Durand-Nicolas-Favre disease
A venereal disease found world-wide, but particularly in tropical and subtropical climates. Now considered a historical term.
Frei's antigen
Antigen produced with pus from patients with lymphogranuloma inguinale. Used in Frei’s test.
Frei's test
Skin test for venereal lymphogranuloma inguinale using Frei’s antigen.
Biography:
Wilhelm Siegmund Frei studied in Freiburg im Breisgau and in Breslau, obtaining his doctorate in Göttingen in 1913. He subsequently worked at the Breslau university medical polyclinic, at the Robert Koch institute in Berlin, at the hygienical institute in Göttingen and at the Breslau university skin clinic. He was habilitated as Privatdozent for dermatology in 1923, becoming professor extraordinary at the Berlin-Spandau Municipal Hospital in 1926. From 1929 he was head physician at the dermatological department of the municipal hospital Berlin-Spandau.
He emigrated to the U.S.A. and became resident physician in dermatology at the Montefiore Hospital, New York, 1937 and 1938.
Frei in particular devoted his efforts to the study of allergic skin diseases, experimental syphilis and the lymphogranulomatosis inguinalis.
Bibliography:
- Ulcus molle, Bakteriologie, Pathologie, Anatomie, Experimentelles.
In Handbuch der Hautkrankheiten. Volume 21; Berlin, 1927.
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