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Edgar Otto Conrad von Gierke
German pathologist, born February 9, 1877, Breslau (Wroclaw), Silesia; died 1945.
Associated eponyms:
Fibiger-Debré von Gierke syndrome
Adrenogenital syndrome of salt loss. An inborn error of metabolism characterized by a deficiency of enzymes involved in the production of adrenocorticosteroid hormones.
Gierke's syndrome
Von Gierke’s is the most common of a group of hereditary glycogen-storage diseases.
Hassall's corpuscles
Spherical or oval eosinophilic bodies present in the medulla of the thymus gland.
Pompe's disease
An extremely rare, progressive, neurodegenerative disorder of childhood causing macroglossia, cardiomegaly and generalized weakness due to excessive storage in skeletal muscle, and hepatomegaly.
Biography:
Edgar Otto Conrad von Gierke studied in Heidelberg, Breslau, and Berlin, receiving his medical doctorate at Heidelberg in 1901. He was subsequently assistant at the university institutes of pathology in Heidelberg, Freiburg, and Berlin, and was habilitated in Freiburg in 1904. After spending some time at the Cancer Institute in London in 1907, he returned to become prosector at the city hospital in Karlsruhe in 1908. In 1910 he became ausserordentlicher professor of bacteriology at the Technische Hochschule in Karlsruhe, and remained in Karlsruhe until his retirement in 1938. When his successor was called up for military service during World War II, however, von Gierke, although seriously ill, took over once more.
von Gierke had a keen sense of humour and a warm heart and in addition to his other talents he was an outstanding sportsman. His outside interests included aviation and mountaineering; he made a solo ascent of the Matterhorn and at the age of 47 years won a gold medal for athletics.
Edgar von Gierke published 68 articles and several books.
Bibliography:
- Taschenbuch der pathologischen Anatomie. Leipzig, 1911; 10th edition, 1929.
- Grundriss der Sektionstechnik.
Freiburg, 1912; 5th edition, 1918.
- Bauchfell.
In Handbuch der pathologischen Anatomie. Volume 4, 1. Berlin, 1926.
- Hepato-nephromegalia glycogenica (Glycogenspeicherkrankheit der Leber und Nieren).
Beiträge zur pathologischen Anatomie und zur allgemeinen Pathologie, Jena, 1929, 82: 497-513.
- W. Gusek:
Die Pathologie in Karlsruhe.
Verhandlungen der Deutschen Gesellschaft für Pathologie, Stuttgart, 1973, 57: 28.
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